Nutrition

How Gut Health Affects Hormones

Discover how gut health influences hormone regulation, including mood, stress, estrogen, and thyroid function. Learn essential tips for maintaining a healthy gut to support overall hormonal balance and improve well-being.

By Sarah Brandow

The connection between gut health and hormones is a complex relationship that plays a crucial role in overall well-being. The gut, often referred to as the "second brain," hosts trillions of microorganisms weighing 3-5 lbs that form the gut microbiome. This microbiome is integral to many bodily functions, including the regulation of hormones.

One of the primary ways the gut influences hormones is through the production and regulation of neurotransmitters. For example, about 90% of serotonin, a hormone that significantly affects mood, is produced in the gut. An imbalance in gut bacteria can disrupt serotonin levels, potentially leading to mood disorders such as depression and anxiety.

The gut microbiome also impacts cortisol, the body's primary stress hormone. Chronic inflammation or dysbiosis (an imbalance in gut bacteria) can lead to elevated cortisol levels, contributing to stress, anxiety, and a weakened immune response. By maintaining a healthy gut, the body can better regulate cortisol production, leading to improved stress management and overall mental health. 

Our food choices play a role in the metabolism of hormones such as estrogen. Certain gut bacteria can influence the reabsorption and excretion of estrogen, affecting hormonal balance. Adequate intake of fiber is important for maintaining healthy estrogen levels because it helps regulate the elimination of excess estrogen from the body. Dietary fiber binds to estrogen in the digestive tract, facilitating its removal through the stool. This prevents reabsorption of estrogen back into the bloodstream, helping to maintain balanced hormone levels. Consuming adequate fiber is essential to reduce the risk of estrogen dominance, which is linked to issues such as weight gain, PMS, endometriosis, and an increased risk of certain cancers. Estrogen dominance in men occurs when there is an imbalance between estrogen and testosterone levels, with estrogen being disproportionately high. This can lead to a variety of symptoms and health issues, including gynecomastia (development of excess breast tissue in men), reduced libido, erectile dysfunction, difficulty adding or loss of muscle mass, fatigue, brain fog, and weight gain around abdomen and chest. 

Gut health is also vital for proper thyroid function. The thyroid gland produces hormones that regulate metabolism, energy levels, and overall hormonal balance. Gut inflammation or an imbalanced microbiome can interfere with the conversion of thyroid hormones, potentially leading to hypothyroidism or other thyroid-related issues.

To maintain a healthy gut and support hormonal balance, it is essential to consume a diet rich in fiber, prebiotic foods, and fermented foods. Regular exercise, adequate sleep, and stress management techniques are also crucial for promoting a healthy gut microbiome. By prioritizing gut health, you can support hormonal regulation and improve your overall well-being. For steps on how to support the gut, take a look at my article on prebiotics (link) and my webinar on gut health (link).

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